Manfred Schoof (6 April 1936 Magdeburg) is a German jazz trumpet player.
He studied music in Kassel and Cologne.
He is a founder of European free jazz and collaborated with Albert Mangelsdorff, Peter Brötzmann, Mal Waldron, and Irčne Schweizer. He is an interpreter of the works (Die Soldaten) of the contemporary composer Bernd Alois Zimmermann.
Schoof won various jazz prices and is involved in the German musical rights association, since 2007 he is chairman of the Union Deutscher Jazzmusiker. He is professor in Cologne since 1990.